Polymerization Studies of Sickle Cell Hemoglobin Incubated in Aqueous Leaf Extract of Nicotiana tabacum Product
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چکیده
منابع مشابه
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15 صفحه اولIntracellular polymerization of sickle hemoglobin. Effects of cell heterogeneity.
To determine the extent to which the broad distribution in intracellular hemoglobin concentrations found in sickle erythrocytes affects the extent of intracellular polymerization of hemoglobin S, we have fractionated these cells by density using discontinuous Stractan gradients. The amount of polymer formed in the subpopulations was experimentally measured as a function of oxygen saturation usi...
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In the last few years. the understanding of the molecular basis of sickle cell disease has progressed rapidly. It is now possible to describe the structure of the gel of polymerized deoxyhemoglobin S at molecular and atomic levels and to begin to understand the mechanism of formation of this gel from hemoglobin solutions. There are several current hypotheses for the pathophysiology of this dise...
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ژورنال
عنوان ژورنال: Research Journal of Medicinal Plant
سال: 2013
ISSN: 1819-3455
DOI: 10.3923/rjmp.2013.92.99